Phu Xuan University Library
|
PXU E-LIB
Sign in
BCHM 355/455: Biochemistry

External

BCHM 355/455: Biochemistry

Biochemical processes sustain life by driving molecular interactions, enzyme activity, and metabolic pathways. Water chemistry, amino acids, and protein structure determine biological function, while enzyme catalysis and thermodynamics regulate energy flow. Metabolic pathways and allosteric control maintain cellular balance.

Biology
Author
Neil Voss
Publisher
Roosevelt University
Source
LibreTexts
License
Mixed
Language
EN
Category
Basic Sciences
Read online Download PDF (open licence)
Contents· 137 sections
  1. 01: Unit 1 - Proteins
  2. 1.01: Molecules of Life
  3. 1.1.01: Cellular Foundations of Biochemistry
  4. 1.1.02: Chemical Foundations
  5. 1.1.03: Physical-Chemical Foundations
  6. 1.1.04: Genetic Foundations
  7. 1.1.05: Essential elements for life
  8. 1.1.06: The Building Blocks of Molecules
  9. 1.1.07: Types of Biological Molecules
  10. 1.1.08: Chapter 1 Questions
  11. 1.1.09: Abiotic Origins of Life
  12. 1.02: Chemistry of Water
  13. 1.2.01: Water
  14. 1.2.02: The multiple roles of water
  15. 1.2.03: pH and Buffers
  16. 1.2.04: Weak Acids and Bases pH and pKa
  17. 1.2.05: Buffering against pH Changes in Biological Systems
  18. 1.2.06: Solubility in an aqueous world - noncovalent interactions in depth
  19. 1.2.07: Solubility in an aqueous world - The Hydrophobic Effect
  20. 1.2.08: Chapter 2 Questions
  21. 1.03: Amino Acids and Peptides
  22. 1.3.01: Amino Acids and Peptides
  23. 1.3.02: Amino Acid Charges
  24. 1.3.03: Cysteine Chemistry
  25. 1.3.04: 3.1-Structure and Property of the Naturally-Occurring Amino Acids
  26. 1.3.05: From Amino Acids to Peptides
  27. 1.04: Proteins- Structure and Folding
  28. 1.4.01: The Structure of Proteins- An Overview
  29. 1.4.02: Levels of Protein Structure
  30. 1.4.03: Secondary Structure
  31. 1.4.04: Protein folding
  32. 1.4.05: Analyses of Protein Structure
  33. 1.4.06: Protein function domains and cooperativity
  34. 1.4.07: The Three-Dimensional Structure of Proteins
  35. 1.4.7.01: Main Chain Conformations
  36. 1.4.7.02: Secondary Structure and Loops
  37. 1.4.7.03: Tertiary Quaternary and Symmetrical Structures
  38. 1.4.7.04: Secondary Structural Motifs and Domains
  39. 1.4.7.05: Protein with Alpha Alpha-Beta Beta and Little Secondary Structure
  40. 1.4.7.06: Intrinsically Disordered Proteins
  41. 1.4.7.07: Fibrillar Proteins
  42. 1.4.7.08: Protein Folding and Unfolding (Denaturation) - Dynamics
  43. 1.4.7.09: Protein Stability - Thermodynamics
  44. 1.4.7.10: Protein Aggregates - Amyloids Prions and Intracellular Granules
  45. 1.4.7.11: Biomolecular Visualization - Conceptions and Misconceptions
  46. 1.4.7.12: Laboratory Determination of the Thermodynamic Parameters for Protein Denaturation
  47. 1.4.7.13: Predicting Structure and Function of Biomolecules Through Natural Language Processing Tools
  48. 1.4.7.14: Predicting Structure from Sequence and Sequence from Structure Function (New 10 24)
  49. 1.4.7.15: Chapter 4 Questions
  50. 1.4.08: Problems - Predicting Protein Structure and Function Using Machine Learning and AI Programs
  51. 1.05: Protein Purification
  52. 1.5.01: Protein Purification
  53. 1.5.02: Cell Disruption
  54. 1.5.03: Fractionation
  55. 1.5.04: Electrophoresis
  56. 1.5.05: Electrophoresis
  57. 1.5.06: Gel Exclusion Chromatography
  58. 1.5.07: Ion Exchange Chromatography
  59. 1.5.08: Affinity Chromatography
  60. 1.5.09: High Performance Liquid Chromatography (HPLC)
  61. 1.5.10: Histidine Tagging
  62. 1.5.11: Quantification of Protein Concentration
  63. 1.5.12: Binding - Enzyme Linked Immunosorbant Assays (ELISAs)
  64. 02: Unit 2 - Enzymes
  65. 2.01: Enzyme Thermodynamics
  66. 2.1.01: Enzymes
  67. 2.1.02: Enzyme Commission Number
  68. 2.1.03: Endergonic and Exergonic Reactions
  69. 2.1.04: The Laws of Thermodynamics
  70. 2.1.05: Thermodynamics
  71. 2.1.06: Energy in Metabolism
  72. 2.02: Enzyme Kinetics
  73. 2.2.01: Basic Principles of Catalysis
  74. 2.2.02: General Catalytic Strategies
  75. 2.2.03: Enzymatic Reaction Mechanisms
  76. 2.2.04: Cofactors and Catalysis
  77. 2.2.05: Kinetics without Enzymes
  78. 2.2.06: Enzyme Kinetics
  79. 2.2.07: Kinetics with Enzymes
  80. 2.2.08: Derivation of Michaelis-Menten equation
  81. 2.2.09: Enzyme Modulation
  82. 2.2.10: Chymotrypsin - A Model Enzyme
  83. 2.2.11: Zymogen Activation
  84. 2.2.12: Ribozymes - RNA Enzymes
  85. 2.03: Enzyme Inhibition
  86. 2.3.01: Overview of Enzyme Regulation
  87. 2.3.02: Overview of Enzyme Inhibition
  88. 2.3.03: Mechanisms of Enzyme Inhibition
  89. 2.3.04: ProteinLigand Binding and Affinity
  90. 2.04: Enzyme Allostery
  91. 2.4.01: Overview of Allosteric Enzymes
  92. 2.4.02: Hemoglobin and Allosteric Regulation
  93. 2.4.03: Allosteric Regulation
  94. 03: Unit 3 - Macromolecules
  95. 3.01: Carbohydrates
  96. 3.1.01: Carbohydrates overview
  97. 3.1.02: Monosaccharides
  98. 3.1.03: Disaccharides
  99. 3.1.04: Polysaccharides
  100. 3.1.05: Glycoconjugates - Proteoglycans Glycoproteins Glycolipids and Cell Walls
  101. 3.1.06: The Sugar Code and Lectin Decoding
  102. 3.1.07: Chapter 7 Problems
  103. 3.1.08: Chapter 7 Problems - Answer Key
  104. 3.02: Nucleic Acids
  105. 3.2.01: Structure and Function - Nucleic Acids
  106. 3.2.02: Nucleic Acids - Structure and Function
  107. 3.2.03: Nucleic Acids - RNA Structure and Function
  108. 3.2.04: Nucleic Acids - Comparison of DNA and RNA
  109. 3.2.05: Enzymes for Genetic modifications
  110. 3.2.06: DNA Isolation Sequencing and Synthesis
  111. 3.2.07: Bioinformatics
  112. 3.03: Lipids
  113. 3.3.01: Introduction to lipids
  114. 3.3.02: Lipids Aggregates in Water - Micelles and Liposomes
  115. 3.3.03: Structure and Function - Lipids and Membranes
  116. 3.04: Membranes and Membrane Proteins
  117. 3.4.01: Basic Concepts in Membranes
  118. 3.4.02: Membrane Bilayer and Monolayer Assemblies - Structures and Dynamics
  119. 3.4.03: Working with Lipids
  120. 3.4.04: Transport in Membranes
  121. 3.4.05: Problems
  122. 3.4.06: Membranes and Membrane Proteins
  123. 3.4.07: Diffusion Across a Membrane - Passive and Facilitated Diffusion
  124. 3.4.08: Diffusion Across a Membrane - Channels
  125. 3.4.09: Diffusion Across a Membrane - Pores
  126. 3.4.10: Active Transport
  127. 04: Biochemistry of Our Senses
  128. 4.01: Cell Signaling
  129. 4.02: Ligand-gated Ion Channel Receptors
  130. 4.03: Nuclear Hormone Receptors
  131. 4.04: G-protein Coupled Receptors (GPCRs)
  132. 4.05: Receptor Tyrosine Kinases (RTKs)
  133. 4.06: Gated Ion Channels - Neural Signaling
  134. 4.07: Signal Transduction - Vision and Olfaction
  135. 4.08: Signal Transduction - Taste (Gustation)
  136. 4.09: Signal Transduction - Temperature
  137. 4.10: Signal Transduction - Pressure