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Chem 231A: Methods of Organic Synthesis
This is a university-level chemistry course that focuses on the techniques and strategies used to build organic molecules, emphasizing the construction of carbon frameworks and controlling stereochemistry through various synthetic methods in organic chemistry; essentially, it teaches students how to plan and execute complex organic syntheses.
- Author
- Jared Shaw
- Publisher
- University of California, Davis
- Source
- LibreTexts
- License
- CC BY-NC-SA
- Language
- EN
- Category
- Basic Sciences
Contents· 36 sections
- 01: Retrosynthetic Analysis
- 1.01: Chiral Pool Molecules
- 1.02: Common Synthetic Equivalents
- 1.03: Examples
- 1.04: Guidelines
- 1.05: Terminology
- 02: Conformational Analysis
- 2.01: Acyclic Conformations
- 2.02: Cyclic Conformations
- 03: Diels-Alder Reaction
- 04: Enolates
- 4.01: Acid Derivative Enolates
- 4.02: Dicarbonyl Chemistry
- 4.03: Ketone Enolates
- 4.04: The aldol reaction
- 05: Oxidations
- 5.01: Oxidation of activated CH bonds
- 5.02: Oxidation of Alcohols
- 5.03: Oxidation of Aldehydes
- 06: Protecting Groups
- 6.01: Alcohol Protecting Groups
- 6.02: Amine Protecting Groups
- 6.03: Carbonyl Protecting Groups
- 6.04: Diol Protecting Groups
- 07: Reductions
- 7.01: Reduction of Acid Derivatives
- 7.02: Reduction of Alcohols
- 7.03: Reduction of Aldehydes and Ketones
- 08: Synthetic Efficiency
- 09: Unstabilized Carbon Nucleophiles
- 9.01: Addition to Carbonyl Compounds
- 9.02: Alkylations
- 9.03: Cuprates
- 9.04: Diastereoselective Addition to Aldehydes and Ketones
- 9.05: Ketone Synthesis
- 9.06: Preparation of Organometallic Reagents