Phu Xuan University Library
|
PXU E-LIB
Sign in
Online Open Genetics

External

Online Open Genetics

Genetics is the scientific study of heredity and the variation of inherited characteristics. It includes the study of genes, themselves, how they function, interact, and produce the visible and measurable characteristics we see in individuals and populations of species as they change from one generation to the next, over time, and in different environments.

GeneticsBiology
Author
Todd Nickle and Isabelle Barrette-Ng
Publisher
Mount Royal University & University of Calgary
Source
LibreTexts
License
CC BY-SA
Language
EN
Category
Basic Sciences
Read online Download PDF (open licence)
Contents· 126 sections
  1. 01: Overview DNA and Genes
  2. 1.01: Overview
  3. 1.02: DNA is the Genetic Material
  4. 1.03: The Structure of DNA
  5. 1.04: Genes are the Basic Units of Inheritance
  6. 1.05: The Function of Genes
  7. 1.06: The Nuclear Genome
  8. 1.07: Model Organisms Facilitate Genetic Advances
  9. 1.E: Overview DNA and Genes (Exercises)
  10. 1.S: Overview DNA and Genes (Summary)
  11. 02: Chromosomes Mitosis and Meiosis
  12. 2.01: DNA is Packaged into Chromatin
  13. 2.02: Mitosis
  14. 2.03: Meiosis
  15. 2.04: The Cell Cycle and Changes in DNA Content
  16. 2.05: Karyotypes Describe Chromosome Number and Structure
  17. 2.06: Polyploidy Arises from Changes in Whole Sets of Chromosomes
  18. 2.07: Endoreduplication
  19. 2.08: Gene Balance
  20. 2.09: Organellar Genomes
  21. 2.E: Chromosomes Mitosis and Meiosis (Exercises)
  22. 2.S: Chromosomes Mitosis and Meiosis (Summary)
  23. 03: Genetic Analysis of Single Genes
  24. 3.01: Mendels First Law
  25. 3.02: Relationships Between Genes Genotypes and Phenotypes
  26. 3.03: Biochemical Basis of Dominance
  27. 3.04: Crossing Techniques Used in Classical Genetics
  28. 3.05: Sex-Linkage- An Exception to Mendels First Law
  29. 3.06: Phenotypes May Not Be As Expected from the Genotype
  30. 3.07: Phenotypic Ratios May Not Be As Expected
  31. 3.E: Genetic Analysis of Single Genes (Exercises)
  32. 3.S: Genetic Analysis of Single Genes (Summary)
  33. 04: Mutation and Variation
  34. 4.01: Mutation and Polymorphism
  35. 4.02: Origins of Mutations
  36. 4.03: Genetic screening for mutations- Forward genetics
  37. 4.04: Types of Mutations
  38. 4.05: Some mutations may not have detectable phenotypes
  39. 4.06: Complementation tests and Allelism
  40. 4.07: Example of Human Mutations
  41. 4.E: Mutation and Variation (Exercises)
  42. 4.S: Mutation and Variation (Summary)
  43. 05: Pedigrees and Populations
  44. 5.01: Prelude to Pedigrees and Populations
  45. 5.02: Pedigree Analysis
  46. 5.03: Inferring the Mode of Inheritance
  47. 5.04: Sporadic and Non-Heritable Diseases
  48. 5.05: Calculating Probabilities
  49. 5.06: Population Genetics
  50. 5.E: Pedigrees and Populations (Exercises)
  51. 5.S: Pedigrees and Populations (Summary)
  52. 06: Genetic Analysis of Multiple Genes
  53. 6.01: Dihybrid Crosses
  54. 6.02: Epistasis and Other Gene Interactions
  55. 6.03: Example of Multiple Genes Affecting One Character
  56. 6.E: Genetic Analysis of Multiple Genes (Exercises)
  57. 6.S: Genetic Analysis of Multiple Genes (Summary)
  58. 07: Linkage and Mapping
  59. 7.01: Linkage
  60. 7.02: Recombination
  61. 7.03: Linkage Reduces Recombination Frequency
  62. 7.04: Crossovers Allow Recombination of Linked Loci
  63. 7.05: Inferring Recombination From Genetic Data
  64. 7.06: Genetic Mapping
  65. 7.07: Mapping With Three-Point Crosses
  66. 7.E: Linkage and Mapping (Exercises)
  67. 7.S: Linkage and Mapping (Summary)
  68. 08: Techniques of Molecular Genetics
  69. 8.01: Prelude to Molecular Genetics
  70. 8.02: Isolating Genomic DNA
  71. 8.03: Isolating or Detecting a Specific Sequence by PCR
  72. 8.04: Cutting and Pasting DNA- Restriction Digests and DNA Ligation
  73. 8.05: Cloning DNA - Plasmid Vectors
  74. 8.06: DNA Analysis - Gel Electrophoresis
  75. 8.07: DNA Analysis- Blotting and Hybridization
  76. 8.08: Transgenic organisms
  77. 8.09: Techniques of Molecular Genetics (Exercises)
  78. 8.S: Techniques of Molecular Genetics (Summary)
  79. 09: Changes in Chromosome Number and Structure
  80. 9.01: Changes in Chromosome Number
  81. 9.02: Changes in Chromosome Structure
  82. 9.03: Chromosome Abnormalities in Humans
  83. 9.04: Diagnosing Human Chromosome Abnormalities
  84. 9.E: Changes in Chromosome Number and Structure (Exercises)
  85. 9.S: Changes in Chromosome Number and Structure (Summary)
  86. 10: Molecular Markers and Quantitative Traits
  87. 10.01: Some Variations in the Genome Affect Complex Traits
  88. 10.02: Origins of Molecular Polymorphisms
  89. 10.03: Classification and Detection of Molecular Markers
  90. 10.04: Applications of Molecular Markers
  91. 10.05: Quantitative Trait Locus (QTL) Analysis
  92. 10.E: Molecular Markers and Quantitative Traits (Exercises)
  93. 10.S: Molecular Markers and Quantitative Traits (Summary)
  94. 11: Genomics and Systems Biology
  95. 11.01: Omics Technologies
  96. 11.02: DNA Sequencing
  97. 11.03: Whole Genome Sequencing
  98. 11.04: Functional Genomics Determining Function(s)
  99. 11.E: Genomics and Systems Biology (Exercises)
  100. 11.S: Genomics and Systems Biology (Summary)
  101. 12: Regulation of Gene Expression
  102. 12.01: The lac Operon
  103. 12.02: The Use of Mutants to Study the lac Operon
  104. 12.03: Eukaryotic Gene Regulation
  105. 12.04: Regulatory Elements in Evolution
  106. 12.05: Additional Levels of Regulating Transcription
  107. 12.06: Epigenetics
  108. 12.07: Regulation of Gene Expression (Exercises)
  109. 12.S: Regulation of Gene Expression (Summary)
  110. 13: Cancer Genetics
  111. 13.01: Classification of Cancers
  112. 13.02: Cancer Cell Biology
  113. 13.03: Hallmarks of Cancer
  114. 13.04: Mutagens and Carcinogens
  115. 13.05: Oncogenes
  116. 13.06: Tumor Suppressor Genes
  117. 13.07: The Poster Boy of Genetic Research Leading to a Cancer Treatment Gleevec (Imatinib)
  118. 13.E: Cancer Genetics (Exercises)
  119. 13.S: Cancer Genetics (Summary)
  120. 14: Appendices
  121. 14.01: Why Use Nomenclature
  122. 14.02: Biochemistry of GeneBehavior
  123. 14.03: Basic Nomenclature
  124. 14.04: Three-Letter Symbols
  125. 14.05: Linked Genes
  126. 14.06: Summary