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Introduction to Genetics

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Introduction to Genetics

Genetics, otherwise known as the Science of Heredity, is the study of biological information, and how this information is stored, replicated, transmitted and used by subsequent generations. The study of genetics can be sub-divided into three main areas: Transmission Genetics, Molecular Genetics, and Population Genetics. In this Introductory text, the focus is on Transmission or Classical Genetics, which deals with the basic principles of heredity and the mechanisms by which traits are passed fro

GeneticsBiology
Author
Natasha Ramroop Singh
Publisher
Thompson Rivers University
Source
LibreTexts
License
CC BY-NC-SA
Language
EN
Category
Basic Sciences
Read online Download PDF (open licence)
Contents· 133 sections
  1. 01: Mendels First Law and Meiosis
  2. 1.01: Introduction
  3. 1.02: Dominant and Recessive Alleles
  4. 1.03: Meiosis
  5. 1.04: One Locus on a Chromosome - Segregation - Monohybrid
  6. 1.05: Punnett Squares - 3-1 Ratio
  7. 1.06: Single Locus Test Crosses
  8. 1.07: Chapter 1 Summary
  9. 1.08: Key Terms in Chapter 1
  10. 1.09: Chapter 1 Study Questions
  11. 1.10: Chapter 1 Answers
  12. 02: Mendels Second Law- Independent Assortment
  13. 2.01: Introduction
  14. 2.02: Two Loci on Different Chromosomes
  15. 2.03: Two Loci on One Chromosome
  16. 2.04: A Dihybrid Cross Showing Mendel's Second Law (Independent Assortment)
  17. 2.05: The Dihybrid Test Cross
  18. 2.06: Predicting Ratios in Genetic Crosses - Rules of Probability
  19. 2.07: Chapter 2 Summary
  20. 2.08: Key Terms in Chapter 2
  21. 2.09: Chapter 2 Study Questions
  22. 2.10: Chapter 2 Answers
  23. 03: The Cell Cycle and Mitosis
  24. 3.01: Introduction
  25. 3.02: The Typical Cell Cycle
  26. 3.03: Mitosis
  27. 3.04: Amount of DNA (c-value) and Number of Chromosomes (n-value)
  28. 3.05: Appearance of a Typical Nuclear Chromosome During the Cell Cycle
  29. 3.06: Compare and Contrast Mitosis and Meiosis
  30. 3.07: Chapter 3 Summary
  31. 3.08: Key Terms in Chapter 3
  32. 3.09: Chapter 3 Study Questions
  33. 3.10: Chapter 3 Answers
  34. 04: Pedigree Analysis
  35. 4.01: Introduction
  36. 4.02: Symbols used in Pedigree Charts
  37. 4.03: Modes of Inheritance
  38. 4.04: Sporadic and Non-Heritable Diseases
  39. 4.05: Calculating Probabilities Using Pedigree Charts
  40. 4.06: Chapter 4 Summary
  41. 4.07: Key Terms in Chapter 4
  42. 4.08: Chapter 4 Study Questions
  43. 4.09: Chapter 4 Answers
  44. 05: The Complementation Test
  45. 5.01: Introduction
  46. 5.02: Complementation Tests and Allelism
  47. 5.03: Complementation Groups Groups of Allelic Mutations
  48. 5.04: Transformation Rescue
  49. 5.05: Chapter 5 Summary
  50. 5.06: Key Terms in Chapter 5
  51. 5.07: Chapter 5 Study Questions
  52. 5.08: Chapter 5 Answers
  53. 06: Alleles at a Single Locus
  54. 6.01: Introduction
  55. 6.02: Somatic vs. Germline Mutations
  56. 6.03: Alleles- Hetero- Homo- Hemizygosity
  57. 6.04: Pleiotropy vs. Polygenic Inheritance
  58. 6.05: Types of Dominance
  59. 6.06: Biochemical Basis of Dominance
  60. 6.07: Classification of Mutants
  61. 6.08: Muller's Morphs
  62. 6.09: Chapter 6 Summary
  63. 6.10: Key Terms in Chapter 6
  64. 6.11: Chapter 6 Study Questions
  65. 6.12: Chapter 6 Answers
  66. 07: The Central Dogma - Mutations and Biochemical Pathways
  67. 7.01: Introduction
  68. 7.02: The Beadle and Tatum Experiments
  69. 7.03: The One Gene- One Enzyme Hypothesis
  70. 7.04: Genetic Screening and Biochemical Pathways
  71. 7.05: Mutations Without Detectable Phenotypes
  72. 7.06: Cystic Fibrosis in Humans
  73. 7.07: Chapter 7 Summary
  74. 7.08: Key Terms in Chapter 7
  75. 7.09: Chapter 7 Study Questions
  76. 7.10: Chapter 7 Answers
  77. 08: Gene Interactions
  78. 8.01: Introduction
  79. 8.02: Recall - Mendelian Dihybrid Crosses
  80. 8.03: Epistasis and Other Gene Interactions
  81. 8.04: Polygenic Inheritance
  82. 8.05: Environmental Factors
  83. 8.06: Factors Causing Deviation from Mendelian Phenotypic Ratios
  84. 8.07: Chapter 8 Summary
  85. 8.08: Key Terms in Chapter 8
  86. 8.09: Chapter 8 Study Questions
  87. 8.10: Chapter 8 Answers
  88. 09: Linkage and Recombination Frequency
  89. 9.01: Introduction
  90. 9.02: Review of Genetic Nomenclature and Symbols
  91. 9.03: Recombination and Recombination Frequency
  92. 9.04: Coupling and Repulsion (cis and trans) Configuration
  93. 9.05: Unlinked Genes vs. Partial Linkage vs. Complete Linkage
  94. 9.06: Experimental Determination of Recombination Frequency
  95. 9.07: Chapter 9 Summary
  96. 9.08: Key Terms in Chapter 9
  97. 9.09: Chapter 9 Study Questions
  98. 9.10: Chapter 9 Answers
  99. 10: Sex Chromosomes Sex Linkage
  100. 10.01: Introduction
  101. 10.02: Autosomes and Sex Chromosomes
  102. 10.03: Pseudo-Autosomal Regions on the X and Y Chromosomes
  103. 10.04: Sex Linkage- An Exception to Mendel's First Law
  104. 10.05: Y-Linked Genes
  105. 10.06: Chapter 10 Summary
  106. 10.07: Key Terms in Chapter 10
  107. 10.08: Chapter 10 Study Questions
  108. 10.09: Chapter 10 Answers
  109. 11: Recombination Mapping of Gene Loci
  110. 11.01: Introduction
  111. 11.02: Genetic Mapping
  112. 11.03: Two-Point and Three-Point Crosses
  113. 11.04: Coincidence and Interference
  114. 11.05: Chapter 11 Summary
  115. 11.06: Key Terms in Chapter 11
  116. 11.07: Chapter 11 Study Questions
  117. 11.08: Chapter 11 Answers
  118. 12: Physical Mapping of Chromosomes and Genomes
  119. 12.01: Introduction
  120. 12.02: Genetic Maps
  121. 12.03: Cytogenetic Maps
  122. 12.04: Physical Maps
  123. 12.05: Chapter 12 Summary
  124. 12.06: Key Terms in Chapter 12
  125. 12.07: Chapter 12 Study Questions
  126. 12.08: Chapter 12 Answers
  127. 13: Genes and COVID-19 Susceptibility in Humans
  128. 13.01: Introduction
  129. 13.02: How Does SARS-Cov-2 Infect Humans
  130. 13.03: Genes Implicated in Severe COVID-19 Infection in Humans
  131. 13.04: Approaches for Vaccine Development Against SARSCov2
  132. 13.05: Chapter 13 Summary
  133. 13.06: Key Terms in Chapter 13