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Klein and Straumanis Guided
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- EN
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- Basic Sciences
Contents· 492 sections
- 01: A Review of General Chemistry - Electrons Bonds and Molecular Properties
- 1.01: Introduction to Organic Chemistry
- 1.02: 1-3 Atomic Orbitals and Hybridization
- 1.2.01: (sp) Hybrid Orbitals and the Structure of Acetylene
- 1.2.02: (sp2) Hybrid Orbitals and the Structure of Ethylene
- 1.2.03: (sp3) Hybrid Orbitals and the Structure of Ethane
- 1.2.04: (sp3) Hybrid Orbitals and the Structure of Methane
- 1.03: Valence Bond Theory
- 1.04: Molecular Orbital Theory
- 1.05: Intermolecular Forces and Physical Properties
- 1.06: Solubility
- 1.07: 1-2 Electron-Dot Model of Bonding- Lewis Structures and Formal Charges
- 1.08: 1-4 Determining Molecular Shape
- 1.09: 1-5 Dipole Moments and Molecular Polarity
- 1.9.01: Polar Covalent Bonds- Electronegativity
- 1.9.02: Polar Covalent Bonds- Dipole Moments
- 1.10: 1-6 Induction and Polar Covalent Bonds
- 1.10.01: Noncovalent Interactions Between Molecules
- 1.E: A Review of General Chemistry (Exercises)
- 02: Molecular Representations
- 2.01: Molecular Representations
- 2.02: Bond-Line Structures
- 2.03: 2.2 Polar Covalent Bonds- Dipole Moments
- 2.04: Identifying Functional Groups
- 2.05: Carbon Atoms with Formal Charges
- 2.06: Identifying Lone Pairs
- 2.07: Three-Dimensional Bond-Line Structures
- 2.08: 2-2 Introduction to Resonance
- 2.8.01: Building Resonance Structures
- 2.8.02: Rules for Resonance Forms
- 2.09: Curved Arrows
- 2.10: Formal Charges in Resonance Structures
- 2.11: Assessing Relative Importance of Resonance Structures
- 2.12: Delocalized and Localized Lone Pairs
- 2.13: 2-1 Drawing Chemical Structures
- 2.14: 2-3 Drawing Resonance Structures
- 2.14.01: Drawing Resonance Forms Using Pattern Recognition
- 2.E: Molecular Representations (Exercises)
- 03: Acids and Bases
- 3.01: 1.21 How the Structure of an Acid Affects its pka Value
- 3.02: An Introduction to Brnsted-Lowry Acids and Bases
- 3.03: Flow of Electron Density - Curved Arrow Notation
- 3.04: Brnsted-Lowry Acidity - A Quantitative Perspective
- 3.05: Brnsted-Lowry Acidity - Qualitative Perspective
- 3.06: Position of Equilibrium and Choice of Reagents
- 3.07: Choice of Solvent
- 3.08: Solvating Effects
- 3.09: Counterions
- 3.10: Lewis Acids and Bases
- 3.11: Hydrogen Bonds
- 3.12: 3-1 Physical properties of organic compounds
- 3.13: 3-3 Acids and Bases Electrophiles and Nucleophiles
- 3.14: 3-4 Organic Acids and Bases
- 3.15: 3-5 How to Predict the Outcome of an Acid-Base Reaction
- 3.16: 3-6 How Substituents Affect the Strength of an Acid
- 3.17: 3-7 Factors That Determine Acid Strength
- 3.E: Acids and Bases (Exercises)
- 04: Alkanes and Cycloalkanes
- 4.01: 3.5 Properties of Alkanes
- 4.02: 3-1 Conformations of open-chain organic molecules
- 4.2.01: Alkanes and Their Stereochemistry
- 4.03: 3-2 Conformations of cyclic organic molecules
- 4.3.01: Conformations of Cyclohexane
- 4.04: Introduction to Alkanes
- 4.05: Nomenclature of Alkanes
- 4.06: Constitutional Isomers of Alkanes
- 4.07: Relative Stability of Isomeric Alkanes
- 4.08: Sources and Uses of Alkanes
- 4.09: Drawing Newman Projections
- 4.10: Cycloalkanes
- 4.11: Conformations of Cyclohexane
- 4.12: Drawing Chair Conformations
- 4.13: Monosubstituted Cyclohexane
- 4.14: Disubstituted Cyclohexane
- 4.15: cis-trans Stereoisomerism
- 4.16: Polycyclic Systems
- 4.17: 4-1 Naming Alkanes
- 4.18: 4-2 Naming Cycloalkanes
- 4.19: 4-3 Cis-Trans Isomerism in Cycloalkanes
- 4.20: 4-4 Alkanes and Alkane Isomers
- 4.21: 4-5 Combustion. Heats of Reaction. Bond Energies
- 4.E: Alkanes and Cycloalkanes (Exercises)
- 05: Stereoisomerism
- 5.01: Prelude to Stereoisomerism
- 5.02: Overview of Isomerism
- 5.03: Introduction to Stereoisomerism
- 5.04: Designating Configuration Using the Cahn-Ingold-Prelog System
- 5.05: Optical Activity
- 5.06: 5-4 Stereoisomeric Relationships - Enantiomers and Diastereomers
- 5.6.01: 001 Pasteur's Discovery of Enantiomers
- 5.6.02: Diastereomers
- 5.6.03: Meso Compounds
- 5.07: Symmetry and Chirality
- 5.08: Fischer Projections
- 5.09: Conformationally Mobile Systems
- 5.10: Resolution of Enantiomers
- 5.11: Chiral Molecules
- 5.12: 5-1 Looking Glass ChemistryChiral and Achiral Molecules
- 5.13: 5-2 The Reason for Handedness in Molecules- Chirality
- 5.14: 5-3 Optical Activity
- 5.15: 5-5 Sequence Rules for Specifying Configuration
- 5.15.01: Diastereomers and Fischer Projections
- 5.E: Stereoisomerism (Exercises)
- 06: Chemical Reactivity and Mechanisms
- 6.01: Enthalpy
- 6.02: Entropy
- 6.03: Gibbs Free Energy
- 6.04: Equilibria
- 6.05: Kinetics
- 6.06: Reading Energy Diagrams
- 6.07: Mechanisms and Arrow Pushing
- 6.08: Combining the Patterns of Arrow Pushing
- 6.09: Catalysts
- 6.10: Drawing Curved Arrows
- 6.11: Carbocation Rearrangements
- 6.12: Nucleophiles and Electrophiles
- 6.13: 6-10 Describing a Reaction- Intermediates
- 6.14: 6-11 Reaction Mechanisms Involving Polar Functional Groups- Using Electron-Pushing' Arrows
- 6.15: 6-1 Writing Equations for Organic Reactions
- 6.16: 6-2 Kinds of Organic Reactions
- 6.17: 6-3 Bond Breaking and Bond Making
- 6.18: 6-4 Bond Dissociation Energy
- 6.19: 6-5 Thermodynamics
- 6.20: 6-6 Enthalpy and Entropy
- 6.21: 6-7 Energy Diagrams
- 6.22: 6-8 Energy Diagram for a Two-Step Reaction Mechanism
- 6.23: 6-9 Kinetics
- 6.E: Chemical Reactivity and Mechanisms (Exercises)
- 07: Substitution Reactions
- 7.01: 7-2 The (S N2) Reaction
- 7.02: 7-3 Characteristics of the (S N2) Reaction
- 7.03: 7-4 The (S N1) Reaction
- 7.04: 7-5 Characteristics of the (S N1) Reaction
- 7.05: Introduction to Substitution Reactions
- 7.06: Alkyl Halides
- 7.07: Possible Mechanisms for Substitution Reactions
- 7.08: The SN2 Mechanism
- 7.09: The SN1 Mechanism
- 7.10: Drawing the Complete Mechanism of an SN1 Reaction
- 7.11: Drawing the Complete Mechanism of an SN2 Reaction
- 7.12: Determining Which Mechanism Predominates
- 7.13: Selecting Reagents to Accomplish Functional Group Transformation
- 7.14: 7-7 When Is the Mechanism (S N1) or (S N2)
- 7.15: 7-1 Introduction to Nucleophilic Substitution Reactions
- 7.16: 7-8 Carbocation Structure and Stability
- 7.17: 7-9 Carbocation Stability
- 7.18: 7-6 Structural and Solvent Effects in (S N) Reactions
- 7.E: Substitution Reactions (Exercises)
- 08: Alkenes- Structure and Preparation via Elimination Reactions
- 8.01: Introduction to Elimination Reactions
- 8.02: Alkenes in Nature and in Industry
- 8.03: Nomenclature of Alkenes
- 8.04: Stereoisomerism in Alkenes
- 8.05: Alkene Stability
- 8.06: Possible Mechanisms for Elimination
- 8.07: The E2 Mechanism
- 8.08: Drawing the Products of an E2 Reaction
- 8.09: The E1 Mechanism
- 8.10: Drawing the Complete Mechanism of an E1 Process
- 8.11: Drawing the Complete Mechanism of an E2 Process 372
- 8.12: Substitution vs. Elimination- Identifying the Reagent
- 8.13: Substitution vs. Elimination- Identifying the Mechanism(s)
- 8.14: Substitution vs. Elimination- Predicting the Products
- 8.15: 8-1 Elimination Reactions- Zaitsev's Rule
- 8.16: 8-1 Nucleophilic Character of the Pi Bond- Electrophilic Addition of Hydrogen Halides
- 8.17: 8-3 The E2 Reaction and the Deuterium Isotope Effect
- 8.18: 8-2 Unimolecular Elimination- E1
- 8.19: 8-4 The E2 Reaction and Cyclohexane Conformation
- 8.20: 8-5 Keys to Success- Substitutin Versus Elimination-Structure Determines Function
- 8.E: Alkenes (Exercises)
- 09: Addition Reactions of Alkenes
- 9.01: Vicinal SYn Dihydroxylation with Osmium Tetroxide
- 9.02: Oxidative Cleavage- Ozonolysis
- 9.03: 9-6 Halogenation of Alkenes- Addition of (X 2)
- 9.04: 9-10 Hydration of Alkenes- Addition of (H 2O) by Hydroboration
- 9.05: Introduction to Addition Reactions
- 9.06: Addition vs. Elimination - A Thermodynamic Perspective
- 9.07: Hydrohalogenation
- 9.08: Acid-Catalyzed Hydration
- 9.09: Oxymercuration-Demercuration
- 9.10: Hydroboration-Oxidation
- 9.11: Catalytic Hydrogenation
- 9.12: Halogenation and Halohydrin Formation
- 9.13: Anti Dihydroxylation
- 9.14: Syn Dihydroxylation
- 9.15: Oxidative Cleavage
- 9.16: Predicting Products of an Addition Reaction
- 9.17: Synthesis Strategies
- 9.18: 9-10 Reduction of Alkenes- Hydrogenation
- 9.19: 9-11 Catalytic Hydrogenation
- 9.20: 9-12 Reduction of Alkynes
- 9.21: 9-13 Oxidation of Alkenes- Cleavage to Carbonyl Compounds
- 9.22: 9-14 Naming Alkenes
- 9.23: 9-15 Cis-Trans Isomerism in Alkenes
- 9.24: 9-16 Sequence Rules- The EZ Designation
- 9.25: 9-1 Nucleophilic Character of the Pi Bond- Electrophilic Addition of Hydrogen Halides
- 9.26: 9-2 Alcohol Synthesis by Electrophilic Hydration- Thermodynamic Control
- 9.27: 9-3 Oxymercuration-Demercuration- A Special Elcctrophilic Addition
- 9.28: 9-4 Hydroboration-Oxidation- A Stereospecific Anti-Markovnikov Hydration
- 9.29: 9-7 Halohydrins from Alkenes- Addition of HOX
- 9.30: 9-8Radical Additions- Anti-Markovnikov Product Formation
- 9.31: 9-8 Oxacyclopropane ( Epoxide) Synthesis- Epoxidation by Peroxycarboxylic Acids
- 9.32: 9-9 Oxidation of Alkenes- Epoxidation and Hydroxylation
- 9.E: Addition Reactions of Alkenes (Exercises)
- 10: Alkynes
- 10.01: Alkylation of Terminal Alkynes
- 10.02: Synthesis Strategies
- 10.03: Introduction to Alkynes
- 10.04: Nomenclature of Alkynes
- 10.05: Acidity of Acetylene and Terminal Alkynes
- 10.06: Preparing Alkynes
- 10.07: Reduction of Alkynes
- 10.08: Hydrohalogenation of Alkynes
- 10.09: Hydration of Alkynes
- 10.10: Halogenation of Alkynes
- 10.11: Ozonolysis of Alkynes
- 10.12: 10-1 Naming Alkynes
- 10.13: 10-2 Alkyne Acidity- Formation of Acetylide Anions
- 10.14: 10-3 Alkylation of Acetylide Anions
- 10.15: 10-4 Preparation of Alkynes- Elimination Reactions of Dihalides
- 10.16: 10-6 Oxidative Cleavage of Alkynes
- 10.17: 10-7 Hydration of Triple Bonds
- 10.18: 10-8 HydroborationOxidation
- 10.19: 10-5 Reactions of Alkynes- Addition of HX and (X 2)
- 10.E: Alkynes (Exercises)
- 11: Radical Reactions
- 11.01: Radicals
- 11.02: Common Patterns in Radical Mechanisms
- 11.03: Chlorination of Methane
- 11.04: Thermodynamic Considerations for Halogenation Reactions
- 11.05: Regioselectivity of Halogenation
- 11.06: Stereochemistry of Halogenation
- 11.07: Allylic Bromination
- 11.08: Atmospheric Chemistry and the Ozone Layer
- 11.09: Autooxidation and Antioxidants
- 11.10: Addition of HBr- Anti-Markovnikov Addition
- 11.11: Radical Polymerization
- 11.12: Radical Processes in the Petrochemical Industry
- 11.13: Halogenation as a Synthetic Technique
- 11.14: 11-1 Preparing Alkyl Halides from Alkanes- Radical Halogenation
- 11.15: 11-2 Chlorination of Methane- The Radical Chain Mechanism
- 11.16: 11-3 Selectivity in Radical Halogenation with Fluorine and Bromine
- 11.17: 11-4 Radical Halogenation at an Allylic Carbon
- 11.18: 11-5 Radical chain reactions
- 11.19: 11-6Radical Additions- Anti-Markovnikov Product Formation
- 11.E: Radical Reactions (Exercises)
- 12: Synthesis
- 12.01: One-Step Syntheses
- 12.02: Retrosynthetic Analysis
- 12.03: Practical Tips for Increasing Proficiency
- 12.04: An Introduction to Organic Synthesis
- 12.05: Building the Carbon Skeleton
- 12.06: The Logic of Synthesis
- 12.E: Synthesis (Exercises)
- 13: Alcohols and Phenols
- 13.01: Physical Properties of Alcohols Hydrogen Bonding
- 13.02: Preparation of Alcohols via Reduction
- 13.03: Preparation of Diols
- 13.04: Reactions of Alcohols - Substitution and Elimination
- 13.05: Reactions of Alcohols- Oxidation
- 13.06: Biological Redox Reactions
- 13.07: Oxidation of Phenol
- 13.08: Synthesis Strategies
- 13.09: Physical Properties of Alcohols Hydrogen Bonding
- 13.10: Acidity of Alcohols and Phenols
- 13.11: Synthesis of Alcohols - Review
- 13.12: Dehydration Reactions of Alcohols
- 13.13: Oxidation Reactions of Alcohols
- 13.14: Alcohols from Reaction of Carbonyl Compounds- Grignard Reagents
- 13.15: 13.7 Reactions of Alcohols
- 13.16: Protection of Alcohols
- 13.17: 13.9 Alcohols from Carbonyl Compounds- Reduction
- 13.E: Alcohols and Phenols (Exercises)
- 14: Ethers and Epoxides Thiols and Sulfides
- 14.01: Introduction to Ethers
- 14.02: Nomenclature of Ethers
- 14.03: Crown Ethers
- 14.04: Nomenclature of Epoxides
- 14.05: Enantioselective Epoxidation
- 14.06: Reactions of Epoxides - Ring-opening
- 14.07: Thiols and Sulfides
- 14.08: Synthesis Strategies Involving Epoxides
- 14.09: Names and Properties of Ethers
- 14.10: Synthesis of Ethers
- 14.11: Reactions of Ethers - Acidic Cleavage
- 14.E: Ethers and Epoxides Thiols and Sulfides (Exercises)
- 15: Infrared Spectroscopy and Mass Spectrometry
- 15.01: 6-1 Spectroscopy and the Electromagnetic Spectrum
- 15.02: 6-2 Infrared Spectroscopy
- 15.03: 6-3 Interpreting Infrared Spectra
- 15.04: 6-4 Infrared Spectra of Some Common Functional Groups
- 15.05: 6-5 Mass Spectrometry of Small Molecules- Magnetic-Sector Instruments
- 15.5.01: Mass Spectroscopy in Further Detail
- 15.06: 6-6 Interpreting Mass Spectra
- 15.07: 6-7 Mass Spectrometry of Some Common Functional Groups
- 15.08: 6-8 Isotopes in Mass Spectrometry
- 15.09: 6-9 Fragmentation Patterns of Organic Molecules
- 15.9.01: More Fragmentation
- 16: Nuclear Magnetic Resonance Spectroscopy
- 16.01: Introduction to NMR Spectroscopy
- 16.02: Acquiring a H NMR Spectrum
- 16.03: Characteristics of a H NMR Spectrum
- 16.04: Number of Signals
- 16.05: Chemical Shift
- 16.06: Integration
- 16.07: Multiplicity
- 16.08: Using H NMR Spectroscopy to Distinguish between Compounds
- 16.09: Analyzing a H NMR Spectrum
- 16.10: Acquiring a C NMR Spectrum
- 16.11: Chemical Shifts in C NMR Spectroscopy
- 16.12: DEPT C NMR Spectroscopy
- 16.13: Drawing the Expected H NMR Spectrum of a Compound
- 16.14: 16-10 Integration of H NMR Absorptions- Proton Counting
- 16.15: 16-10 Spin-Spin Splitting in H NMR Spectra
- 16.16: 16-11 More Complex Spin-Spin Splitting Patterns
- 16.17: 16-12 Nuclear Magnetic Resonance Spectroscopy - Extra Details
- 16.18: 16-1 Nuclear Magnetic Resonance Spectroscopy
- 16.19: 16-2 The Nature of NMR Absorptions
- 16.20: 16-3 Chemical Shifts
- 16.21: 16-4 C NMR Spectroscopy- Signal Averaging and FT-NMR
- 16.22: 16-5 Characteristics of C NMR Spectroscopy
- 16.23: 16-6 DEPT C NMR Spectroscopy
- 16.24: 16-7 Uses of C NMR Spectroscopy
- 16.25: 16-8 H NMR Spectroscopy and Proton Equivalence
- 16.26: 16-9 Chemical Shifts in H NMR Spectroscopy
- 16.27: Structure Determination - Nuclear Magnetic Resonance Spectroscopy
- 16.E: Nuclear Magnetic Resonance Spectroscopy (Exercises)
- 17: Conjugated Pi Systems and Pericyclic Reactions
- 17.01: An Introduction to Pericyclic Reactions
- 17.02: MO Description of Cycloadditions
- 17.03: Electrocyclic Reactions
- 17.04: Sigmatropic Rearrangements
- 17.05: Electronic Spectra- Ultraviolet and Visible Spectroscopy
- 17.06: Color
- 17.07: The Chemistry of Vision
- 17.08: Introduction
- 17.09: Two Neighboring Double Bonds- Conjugated Dienes
- 17.10: Two Neighboring Double Bonds- Conjugated Dienes and MO Theory
- 17.11: 13- or Conjugated Dienes. Electrophilic and Radical Addition
- 17.12: Electrophilic Attack on Conjugated Dienes-Kinetic and Thermodynamic Control
- 17.13: Kinetic versus Thermodynamic Control
- 17.14: Polymerization Reactions of Conjugated Dienes
- 17.15: The Diels-Alder Cycloaddition
- 17.16: Diels-Alder - a closer look
- 17.17: Electrocyclic Reactions
- 17.E: Conjugated Pi Systems and Pericyclic Reactions (Exercises)
- 18: Aromatic Compounds
- 18.01: Aromaticity and the Huckel 4n 2 Rule
- 18.02: Introduction to Aromatic Compounds
- 18.03: Nomenclature of Benzene Derivatives
- 18.04: Reactions at the Benzylic Position
- 18.05: Reduction of the Aromatic Moiety
- 18.06: Delocalized Electrons Explain Benzenes Structure
- 18.07: Structure and Resonance Energy of Benzene- A First Look at Aromaticity
- 18.08: Spectral Characteristics of the Benzene Ring
- 18.E: Aromatic Compounds (Exercises)
- 19: Aromatic Substitution Reactions
- 19.01: Nitration
- 19.02: Friedel-Crafts Alkylation
- 19.03: Friedel-Crafts Acylation
- 19.04: Halogens - The Exception
- 19.05: Activation or Deactivation by Substituents on a Benzene Ring
- 19.06: Trisubstituted Benzenes - Additivity of Effects
- 19.07: An Explanation of Substituent Effects
- 19.08: Synthesis of Polysubstituted Benzenes
- 19.09: Nucleophilic Aromatic Substitution
- 19.10: Benzyne
- 19.11: Elimination-Addition
- 19.12: 19.15 Identifying the Mechanism of an Aromatic Substitution Reaction
- 19.13: Synthesis of Benzene Derivatives- Electrophilic Aromatic Substitution
- 19.14: Electrophilic Aromatic Substitution Reactions - Bromination
- 19.15: Other Aromatic Substitutions
- 19.16: Substituent Effects in Substituted Aromatic Rings
- 19.17: An Explanation of Substituent Effects
- 19.E: Aromatic Substitution Reactions (Exercises)
- 20: Aldehydes and Ketones
- 20.01: 19.5 Nucleophilic Addition of
- 20.1.01: (H 2O
- 20.1.1.01: 20.4 Nucleophilic Addition of (H 2O)- Hydration
- 20.02: Mechanism Strategies
- 20.03: Sulfur Nucleophiles
- 20.04: Hydrogen Nucleophiles
- 20.05: 20.10 Nucleophilic Addition of Phosphorus Ylides- The Wittig Reaction
- 20.06: Baeyer-Villiger Oxidation of Aldehydes and Ketones
- 20.07: Synthesis Strategies
- 20.08: Spectroscopic Analysis of Aldehydes and Ketones
- 20.09: 20.1 Oxidation of Aldehydes and Ketones
- 20.10: 20.2 Naming Aldehydes and Ketones
- 20.11: 20.3 Preparing Aldehydes and Ketones
- 20.12: Nucleophilic Addition of Alcohols- Acetal Formation
- 20.13: 20.5a Nucleophilic Addition Reactions of Aldehydes and Ketones
- 20.14: Nucleophilic Addition of Amines- Imine and Enamine Formation
- 20.15: 20.7a Nucleophilic Addition of Hydrazin - The Wolff-Kishner Reaction
- 20.E: Aldehydes and Ketones (Exercises)
- 21: Carboxylic Acids and Their Derivatives
- 21.01: 20.2 Naming Carboxylic Acids and Nitriles
- 21.02: 20.3 Structure and Properties of Carboxylic Acids
- 21.03: Introduction to Carboxylic Acids
- 21.04: Nomenclature of Carboxylic Acids
- 21.05: Preparation of Carboxylic Acids
- 21.06: Introduction to Carboxylic Acid Derivatives
- 21.07: 21.10 Chemistry of Esters
- 21.08: Reactions of Esters
- 21.09: 21.12 Chemistry of Amides
- 21.10: 21.13 Preparing Carboxylic Acids
- 21.11: Synthesis Strategies
- 21.12: Spectroscopy of Carboxylic Acids and Their Derivatives
- 21.13: 21.4 Preparing Carboxylic Acids
- 21.14: 21.5 Structure and Properties of Carboxylic Acids
- 21.15: 21.7 Nucleophilic Acyl Substitution Reactions
- 21.16: 21.8 Chemistry of Acid Halides
- 21.17: 21.8 Nucleophilic Acyl Substitution Reactions of Carboxylic Acids
- 21.18: 21.9 Chemistry of Acid Anhydrides
- 21.E: Carboxylic Acids and Their Derivatives (Exercises)
- 22: Alpha Carbon Chemistry- Enols and Enolates
- 22.01: 19.13 Conjugate Nucleophilic Addition to
- 22.1.01: (
- 22.1.1.01: alpha
- 22.1.1.1.01: )
- 22.1.1.1.1.01: (
- 22.1.1.1.1.1.01: beta
- 22.02: 22.1 Intro to Enols and Enolates
- 22.03: Halogenation of Aldehydes and Ketones
- 22.04: 22.3a Carbonyl Condensations - The Aldol Reaction
- 22.05: 22.3b Dehydration of Aldol Products - Synthesis of Enones
- 22.06: 22.4 Claisen Condensation Reactions
- 22.07: Alkylation of the Alpha Position
- 22.08: 22.5 Alkylation of Enolate Ions
- 22.09: 22.6 Conjugate Nucleophilic Addition to (alpha) (beta)-unsaturated Aldehydes and Ketones
- 22.10: Synthesis Strategies
- 22.E: Alpha Carbon Chemistry- Enols and Enolates (Exercises)
- 23: Amines
- 23.01: Introduction to Amines
- 23.02: Preparation of Amines - A Review
- 23.03: Preparation of Amines via Substitution Reactions
- 23.04: Preparation of Amines via Reductive Amination
- 23.05: Synthesis Strategies
- 23.06: Acylation of Amines
- 23.07: The Hofmann Elimination
- 23.08: Reactions of Amines with Nitrous Acid
- 23.09: Reactions of Aryldiazonium Ions
- 23.10: Nitrogen Heterocycles
- 23.11: 23.12 Heterocyclic Amines
- 23.12: Spectroscopy of Amines
- 23.13: 23.2 Naming Amines
- 23.14: 23.3 Basicity of Amines
- 23.15: 23.3 Structure and Properties of Amines
- 23.16: Synthesis of Amines by Alkylation
- 23.17: 23.5 Synthesis of Amines
- 23.E: Amines (Exercises)
- 24: Carbohydrates
- 24.01: Introduction to Carbohydrates
- 24.02: Classification of Monosaccharides
- 24.03: Configuration of Aldoses
- 24.04: Configuration of Ketoses
- 24.05: Cyclic Structures of Monosaccharides
- 24.06: Reactions of Monosaccharides
- 24.07: Disaccharides
- 24.08: Polysaccharides
- 24.09: Amino Sugars
- 24.10: N-Glycosides
- 24.E: Carbohydrates (Exercises)
- 25: Amino Acids Peptides and Proteins
- 25.01: Introduction to Amino Acids Peptides and Proteins
- 25.02: Structure and Properties of Amino Acids
- 25.03: Amino Acid Synthesis
- 25.04: Structure of Peptides
- 25.05: Sequencing a Peptide
- 25.06: Peptide Synthesis
- 25.07: Protein Structure
- 25.08: Protein Function
- 25.E: Amino Acids Peptides and Proteins (Exercises)
- 26: Lipids
- 26.01: Introduction to Lipids
- 26.02: Waxes
- 26.03: Triglycerides
- 26.04: Reactions of Triglycerides
- 26.05: Phospholipids
- 26.06: Steroids
- 26.07: Prostaglandins
- 26.08: Terpenes
- 26.E: Lipids (Exercises)
- 27: Synthetic Polymers
- 27.01: Introduction to Synthetic Polymers
- 27.02: Nomenclature of Synthetic Polymers
- 27.03: Copolymers
- 27.04: Polymer Classification by Reaction Type
- 27.05: Polymer Classification by Mode of Assembly
- 27.06: Polymer Classification by Structure
- 27.07: Polymer Classification by Properties
- 27.08: Polymer Recycling
- 27.E: Synthetic Polymers (Exercises)